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1

Effect of Indacaterol on Dynamic Lung Hyperinflation and Breathlessness in Hyperinflated Patients with COPD

Beeh, Kai-Michael, Wagner, Frank, Khindri, Sanjeev, Drollmann, Anton Franz

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2011

Language:

english

File:

PDF, 223 KB

english, 2011

2

And Then There Were Three: Time to Move Onward in COPD Drug Development Beyond LAMA/LABA/ICS at Last?

Journal:

Pulmonary Therapy

Year:

2018

Language:

english

File:

PDF, 373 KB

english, 2018

3

c-erbB-2 Expression in small-cell lung cancer is associated with poor prognosis

Patrick Micke, Jan Georg Hengstler, Roser Ros, Fernando Bittinger, Tsegay Metz, Susanne Gebhard, Kai Michael Beeh, Franz Oesch, Roland Buhl

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 277 KB

english, 2001

4

Anticholinergika in der Therapie der chronisch-obstruktiven Lungenerkrankung (COPD)

Kai-Michael Beeh, Tobias Welte, Roland Buhl

Journal:

Medizinische Klinik - Intensivmedizin und Notfallmedizin

Year:

2000

Language:

german

File:

PDF, 165 KB

german, 2000

5

Pathogenese des Asthma bronchiale – Eröffnung neuer therapeutischer Perspektiven

Kai-Michael Beeh, Roland Buhl

Journal:

Medizinische Klinik - Intensivmedizin und Notfallmedizin

Year:

2001

Language:

german

File:

PDF, 296 KB

german, 2001

6

Effects of Piclamilast, a Selective Phosphodiesterase-4 Inhibitor, on Oxidative Burst of Sputum Cells From Mild Asthmatics and Stable COPD Patients

Kai M. Beeh, Jutta Beier, Claudia Lerch, Ann K. Schulz, Roland Buhl

Journal:

Year:

2004

Language:

english

File:

PDF, 140 KB

english, 2004

7

Indacaterol, a novel inhaled, once-daily, long-acting beta2-agonist for the treatment of obstructive airways diseases

Kai M. Beeh, Jutta Beier

Journal:

Advances in Therapy

Year:

2009

Language:

english

File:

PDF, 557 KB

english, 2009

8

The short, the long and the “ultra-long”: Why duration of bronchodilator action matters in chronic obstructive pulmonary disease

Kai M. Beeh, Jutta Beier

Journal:

Advances in Therapy

Year:

2010

Language:

english

File:

PDF, 321 KB

english, 2010

9

Erratum to: Indacaterol, a novel inhaled, once-daily, long-acting beta2-agonist for the treatment of obstructive airways diseases

Kai M. Beeh, Jutta Beier

Journal:

Advances in Therapy

Year:

2009

File:

PDF, 93 KB

2009

10

Tolerability and pharmacokinetics of inhaled bimosiamose disodium in healthy males

Michael Meyer, Kai-Michael Beeh, Jutta Beier, Diana Beyer, Ewald Aydt, Rainer Zahlten, Bernd Jilma, Gerhard Wolff

Journal:

British Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 141 KB

english, 2007

11

Induced sputum methodology: validity and reproducibility of total glutathione measurement in supernatant of healthy and asthmatic individuals

Jutta Beier, Kai-Michael Beeh, Oliver Kornmann, Roland Buhl

Journal:

Journal of Laboratory and Clinical Medicine

Year:

2004

Language:

english

File:

PDF, 133 KB

english, 2004

12

Bimosiamose, an inhaled small-molecule pan-selectin antagonist, attenuates late asthmatic reactions following allergen challenge in mild asthmatics: A randomized, double-blind, placebo-controlled clinical cross-over-trial

Kai M. Beeh, Jutta Beier, Michael Meyer, Roland Buhl, Rainer Zahlten, Gerhard Wolff

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2006

Language:

english

File:

PDF, 154 KB

english, 2006

13

Clinical application of a simple questionnaire for the differentiation of asthma and chronic obstructive pulmonary disease

Kai Michael Beeh, Oliver Kornmann, Jutta Beier, Michael Ksoll, Roland Buhl

Journal:

Respiratory Medicine

Year:

2004

Language:

english

File:

PDF, 248 KB

english, 2004

14

Discrepant nasal and bronchial nitric oxide kinetics during early and late phase allergic reactions

Stephanie Korn, Jutta Beier, Charlene Heilmann, Oliver Kornmann, Roland Buhl, Kai Michael Beeh

Journal:

Respiratory Medicine

Year:

2005

Language:

english

File:

PDF, 165 KB

english, 2005

15

Sputum levels of metalloproteinase-9 and tissue inhibitor of metalloproteinase-1, and their ratio correlate with airway obstruction in lung transplant recipients: relation to tumor necrosis factor-α and interleukin-10

Kai Michael Beeh, Jutta Beier, Oliver Kornmann, Patrick Micke, Roland Buhl

Journal:

The Journal of Heart and Lung Transplantation

Year:

2001

Language:

english

File:

PDF, 118 KB

english, 2001

16

Staging small cell lung cancer: Veterans Administration Lung Study Group versus International Association for the Study of Lung Cancer—what limits limited disease?

Micke, Patrick, Faldum, Andreas, Metz, Tsegay, Beeh, Kai-Michael, Bittinger, Fernando, Hengstler, Jan-Georg, Buhl, Roland

Journal:

Year:

2002

Language:

english

File:

PDF, 157 KB

english, 2002

17

Effect of tiotropium vs. salmeterol on exacerbations: GOLD II and maintenance therapy naïve patients

Claus Vogelmeier, Leonardo M. Fabbri, Klaus F. Rabe, Kai-Michael Beeh, Hendrik Schmidt, Norbert Metzdorf, Thomas Glaab

Journal:

Respiratory Medicine

Year:

2013

Language:

english

File:

PDF, 755 KB

english, 2013

18

Tiotropium versus Salmeterol for the Prevention of Exacerbations of COPD

Vogelmeier, Claus, Hederer, Bettina, Glaab, Thomas, Schmidt, Hendrik, Rutten-van Mölken, Maureen P.M.H., Beeh, Kai M., Rabe, Klaus F., Fabbri, Leonardo M.

Journal:

Boston Medical and Surgical Journal

Year:

2011

Language:

english

File:

PDF, 773 KB

english, 2011

19

Increased concentrations of glutathione in induced sputum of patients with mild or moderate allergic asthma

Beier, Jutta, Beeh, Kai Michael, Semmler, David, Beike, Nicole, Buhl, Roland

Journal:

Annals of Allergy, Asthma & Immunology

Year:

2004

Language:

english

File:

PDF, 177 KB

english, 2004

20

Clinical trial design in chronic obstructive pulmonary disease: current perspectives and considerations with regard to blinding of tiotropium

Kai-Michael Beeh, Jutta Beier, James F Donohue

Journal:

Respiratory Research

Year:

2012

Language:

english

File:

PDF, 364 KB

english, 2012

21

A blinded evaluation of the efficacy and safety of glycopyrronium, a once-daily long-acting muscarinic antagonist, versus tiotropium, in patients with COPD: the GLOW5 study

Chapman, Kenneth R, Beeh, Kai-Michael, Beier, Jutta, Bateman, Eric D, D’Urzo, Anthony, Nutbrown, Robert, Henley, Michelle, Chen, Hungta, Overend, Tim, D’Andrea, Peter

Journal:

BMC Pulmonary Medicine

Year:

2014

Language:

english

File:

PDF, 225 KB

english, 2014

22

“All I want for Christmas is Two”: The Advent of Novel Fixed-Combination Inhalers for COPD and Outlook for 2014

Journal:

Advances in Therapy

Year:

2013

Language:

english

File:

PDF, 197 KB

english, 2013

23

Inhaled pan-selectin antagonist Bimosiamose attenuates airway inflammation in COPD

Watz, Henrik, Bock, Daniel, Meyer, Michael, Schierhorn, Katrin, Vollhardt, Karin, Woischwill, Christiane, Pedersen, Frauke, Kirsten, Anne, Beeh, Kai-Michael, Meyer-Sabellek, Wolfgang, Magnussen, Helgo

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2013

Language:

english

File:

PDF, 332 KB

english, 2013

24

The novel TLR-9 agonist QbG10 shows clinical efficacy in persistent allergic asthma

Beeh, Kai-Michael, Kanniess, Frank, Wagner, Frank, Schilder, Cordula, Naudts, Ingomar, Hammann-Haenni, Anya, Willers, Joerg, Stocker, Hans, Mueller, Philipp, Bachmann, Martin F., Renner, Wolfgang A.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2013

Language:

english

File:

PDF, 354 KB

english, 2013

25

Effect of QVA149 on lung volumes and exercise tolerance in COPD patients: The BRIGHT study

Beeh, Kai-Michael, Korn, Stephanie, Beier, Jutta, Jadayel, Dalal, Henley, Michelle, D'Andrea, Peter, Banerji, Donald

Journal:

Respiratory Medicine

Year:

2014

Language:

english

File:

PDF, 494 KB

english, 2014

26

Effect of histamine and adenosine 5′-monophosphate provocation on sputum neutrophils and related mediators in atopic patients

Pohl, Daniel, Beier, Jutta, Buhl, Roland, Beeh, Kai M.

Journal:

Annals of Allergy, Asthma & Immunology

Year:

2005

Language:

english

File:

PDF, 129 KB

english, 2005

27

Tiotropium Respimat® in asthma: a double-blind, randomised, dose-ranging study in adult patients with moderate asthma

Kai-Michael Beeh,Petra Moroni-Zentgraf,Othmar Ablinger…

Journal:

Respiratory Research

Year:

2014

Language:

english

File:

PDF, 233 KB

english, 2014

28

Turning a Molecule into a Medicine: the Development of Indacaterol as a Novel Once-Daily Bronchodilator Treatment for Patients with COPD

Murphy, Lorraine, Rennard, Stephen, Donohue, James, Molimard, Mathieu, Dahl, Ronald, Beeh, Kai-Michael, Dederichs, Juergen, Fülle, Hans-Jürgen, Higgins, Mark, Young, David

Journal:

Year:

2014

Language:

english

File:

PDF, 909 KB

english, 2014

29

Cigarette Smoking, But Not Sensitization to Alternaria , Is Associated with Severe Asthma in Urban Patients

Beeh, Kai-Michael, Micke, Patrick, Ksoll, Michael, Buhl, Roland

Journal:

Journal of Asthma

Year:

2001

Language:

english

File:

PDF, 154 KB

english, 2001

30

Improvement in quality of life with omalizumab in patients with severe allergic asthma

Chipps, Bradley, Buhl, Roland, Beeh, Kai-Michael, Fox, Howard, Thomas, Karen, Reisner, Colin

Journal:

Current Medical Research and Opinion

Year:

2006

Language:

english

File:

PDF, 434 KB

english, 2006

31

Assessing the clinical value of fast onset and sustained duration of action of long-acting bronchodilators for COPD

Cazzola, Mario, Beeh, Kai M., Price, David, Roche, Nicolas

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2015

Language:

english

File:

PDF, 570 KB

english, 2015

32

Aclidinium improves exercise endurance, dyspnea, lung hyperinflation, and physical activity in patients with COPD: a randomized, placebo-controlled, crossover trial

Beeh, Kai M, Watz, Henrik, Puente-Maestu, Luis, de Teresa, Luis, Jarreta, Diana, Caracta, Cynthia, Gil, Esther, Magnussen, Helgo

Journal:

BMC Pulmonary Medicine

Year:

2014

Language:

english

File:

PDF, 759 KB

english, 2014

33

Longitudinal measurement of airway inflammation over one year in children and adults with intermittent asthma

Pedersen, Frauke, Holz, Olaf, Kanniess, Frank, Zielen, Stefan, Schulze, Johannes, Gillissen, Adrian, von Berg, Andrea, Berdel, Dietrich, Beier, Jutta, Beeh, Kai, Schnoor, Maike, Magnussen, Helgo

Journal:

BMC Research Notes

Year:

2014

Language:

english

File:

PDF, 722 KB

english, 2014

34

Allergen-Induced Asthmatic Responses Modified by a GATA3-Specific DNAzyme

Krug, Norbert, Hohlfeld, Jens M., Kirsten, Anne-Marie, Kornmann, Oliver, Beeh, Kai M., Kappeler, Dominik, Korn, Stephanie, Ignatenko, Stanislav, Timmer, Wolfgang, Rogon, Cordelia, Zeitvogel, Jana, Zha

Journal:

New England Journal of Medicine

Year:

2015

Language:

english

File:

PDF, 337 KB

english, 2015

35

Dissimilarity between Seasonal Changes in Airway Responsiveness to Adenosine-5’-Monophosphate and Methacholine in Patients with Grass Pollen Allergic Rhinitis: Relation to Induced Sputum

Beier, Jutta, Beeh, Kai Michael, Kornmann, Oliver, Morankic, Emila, Ritter, Nicole, Buhl, Roland

Journal:

International Archives of Allergy and Immunology

Year:

2003

Language:

english

File:

PDF, 121 KB

english, 2003

36

Sputum Levels of Reduced Glutathione Increase 24 Hours after Allergen Challenge in Isolated Early, but Not Dual Asthmatic Responders

Beier, Jutta, Beeh, Kai Michael, Semmler, David, Buhl, Roland

Journal:

International Archives of Allergy and Immunology

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

37

Characterisation of exacerbation risk and exacerbator phenotypes in the POET-COPD trial

Beeh, Kai M, Glaab, Thomas, Stowasser, Susanne, Schmidt, Hendrik, Fabbri, Leonardo M, Rabe, Klaus F, Vogelmeier, Claus F

Journal:

Respiratory Research

Year:

2013

Language:

english

File:

PDF, 606 KB

english, 2013

38

Is There a Role for Antiinflammatory Treatment in COPD?

Beeh, Kai M., Glaab, Thomas

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2009

Language:

english

File:

PDF, 149 KB

english, 2009

39

The 24-h lung-function profile of once-daily tiotropium and olodaterol fixed-dose combination in chronic obstructive pulmonary disease

Beeh, Kai-Michael, Westerman, Jan, Kirsten, Anne-Marie, Hébert, Jacques, Grönke, Lars, Hamilton, Alan, Tetzlaff, Kay, Derom, Eric

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2015

Language:

english

File:

PDF, 724 KB

english, 2015

40

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] C21. NEW TARGETS FOR ASTHMA THERAPY - Novel TLR-9 Agonist CYT003-QbG10 Shown To Improve Asthma Control In Placebo-Controlled Phase II Clinical Trial

Renner, Wolfgang A., Beeh, Kai-Michael, Schilder, Cordula, Wagner, Frank, Kanniess, Frank, Naudts, Ingomar, Hammann, Anya, Willers, Joerg, Mueller, Philipp, Bachmann, Martin

Year:

2011

Language:

english

File:

PDF, 21 KB

english, 2011

41

Tiotropium and Salmeterol in COPD Patients at Risk of Exacerbations: A Post Hoc Analysis from POET-COPD®

Vogelmeier, Claus F., Asijee, Guus M., Kupas, Katrin, Beeh, Kai M.

Journal:

Advances in Therapy

Year:

2015

Language:

english

File:

PDF, 775 KB

english, 2015

42

Anticholinergics in the Treatment of Chronic Obstructive Pulmonary Disease

Beeh, Kai-Michael, Welte, Tobias, Buhl, Roland

Journal:

Year:

2002

Language:

english

File:

PDF, 103 KB

english, 2002

43

Increased Glutathione Disulfide and Nitrosothiols in Sputum Supernatant of Patients With Stable COPD

Beeh, Kai Michael, Beier, Jutta, Koppenhoefer, Nicole, Buhl, Roland

Journal:

Year:

2004

Language:

english

File:

PDF, 146 KB

english, 2004

44

Seasonal Distribution of COPD Exacerbations in the Prevention of Exacerbations With Tiotropium in COPD Trial

Rabe, Klaus F., Fabbri, Leonardo M., Vogelmeier, Claus, Kögler, Harald, Schmidt, Hendrik, Beeh, Kai M., Glaab, Thomas

Journal:

Year:

2013

Language:

english

File:

PDF, 662 KB

english, 2013

45

Dose-finding evaluation of once-daily treatment with olodaterol, a novel long-acting β2-agonist, in patients with asthma: results of a parallel-group study and a crossover study

O’Byrne, Paul M., D’Urzo, Tony, Beck, Ekkehard, Fležar, Matjaž, Gahlemann, Martina, Hart, Lorna, Blahova, Zuzana, Toorawa, Robert, Beeh, Kai-Michael

Journal:

Respiratory Research

Year:

2015

Language:

english

File:

PDF, 954 KB

english, 2015

46

Randomised, double-blind, placebo-controlled crossover study to investigate different dosing regimens of olodaterol delivered via Respimat® in patients with moderate to severe persistent asthma

Beeh, Kai-Michael, LaForce, Craig, Gahlemann, Martina, Wenz, Arne, Toorawa, Robert, Fležar, Matjaž

Journal:

Respiratory Research

Year:

2015

Language:

english

File:

PDF, 982 KB

english, 2015

47

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] B33. ASTHMA THERAPY: NOVEL APPROACHES - Dose-Finding Study Of 4-Week, Once-Daily Treatment With Olodaterol, A Novel Long-Acting B2-Agonist, In Patients With Asthma

Beeh, Kai-Michael, Beck, Ekkehard, Gahlemann, Martina, Blahova, Zuzana, Toorawa, Robert, Flezar, Matjaz

Year:

2012

Language:

english

File:

PDF, 24 KB

english, 2012

48

Pharmacodynamics and Pharmacokinetics Following Once-Daily and Twice-Daily Dosing of Tiotropium Respimat ® in Asthma Using Standardized Sample-Contamination Avoidance

Beeh, Kai-Michael, Kirsten, Anne-Marie, Dusser, Daniel, Sharma, Ashish, Cornelissen, Piet, Sigmund, Ralf, Moroni-Zentgraf, Petra, Dahl, Ronald

Journal:

Journal of Aerosol Medicine and Pulmonary Drug Delivery

Year:

2016

Language:

english

File:

PDF, 816 KB

english, 2016

49

Long-term Repeatability of Induced Sputum Cells and Inflammatory Markers in Stable, Moderately Severe COPDa

Beeh, Kai M., Beier, Jutta, Kornmann, Oliver, Mander, Annette, Buhl, Roland

Journal:

Year:

2003

Language:

english

File:

PDF, 212 KB

english, 2003

50

Dual bronchodilation for the treatment of chronic obstructive pulmonary disease: a review of the latest clinical data

Banerji, Donald, Fogel, Robert, Beeh, Kai-Michael

Journal:

Clinical Investigation

Year:

2014

Language:

english

File:

PDF, 2.00 MB

english, 2014

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